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Mylotarg(gemtuzumab ozogamicin)吉妥珠单抗 是第1种靶向CD33的急性髓性白血病(AML)治疗药物,该药是一种抗体药物偶联物(ADC),由细胞毒性制剂卡奇霉素(calicheamicin)和靶向CD33的一种单克隆抗体偶联而成。CD33是一种抗原蛋白,在高达90%患者的AML细胞上表达。当Mylotarg结合至细胞表面的CD33抗原时被吸收进入细胞内,释放出卡奇霉素导致细胞死亡。
Mylotarg(gemtuzumab ozogamicin)吉妥珠单抗 是第1种靶向CD33的急性髓性白血病(AML)治疗药物。...
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India Bosheng Pharmacy app is under production with two ends.